Table 2

Treatment responder eyes per group by visit

Treatment responder eyes per group by visit
Group/visitFirst yearSecond yearThird year
0.1% loading dose group responders39 (61%),
Adjusted-p = 0.86*		19 (31%),
Adjusted-p = 0.88*		10 (18%),
Adjusted-p = 1.00*
0.01% group responders40 (69%),
Adjusted-p = 0.76*		22 (38%),
Adjusted-p = 0.82*		12 (21%),
Adjusted-p = 0.87*
Placebo group responders27 (54%)15 (26%)9 (17%)
Eyes less than −5 D per group by visit
Group/visitSecond yearThird year
0.1% loading dose group13 (21%)15 (24%)
0.01% group8 (14%)11 (18%)
Placebo group12 (21%)13 (23%)

  • 0.1% loading dose, participants who received 0.1% loading dose the first 6 months of intervention and then 0.01% for the remaining 18 months of intervention.

  • 0.01% loading dose, participants that received 0.01% for the full 2 years of the intervention.

  • Responders, eyes that experienced less than 0.50 D progression from baseline to the given visit.

  • *Compared to placebo at the given time point.