Parameters analysed for in-vivo confocal microscopy images
| Corneal nerve parameters | |
| Corneal nerve fibre density | Number of fibres/mm2, each frame area=0.16033 mm2 |
| Corneal nerve branch density | Number of branch points on the main fibres/mm2) |
| Corneal nerve fibre length | Total length of fibre mm/mm2 |
| Corneal nerve fibre total branch density | Total number of branch points/mm2 |
| Corneal nerve fibre Aaea | Total nerve fibre area mm2/mm2 |
| Corneal nerve fibre width | Average nerve fibre with mm/mm2 |
| Corneal nerve fibre fractal dimension | Metric of corneal nerve morphology to measure the spatial loss of nerves |
| Corneal neuroma parameters | |
| Area | area/μm2 |
| Average length | μm |
| Perimeter | μm |
| Corneal dendritic cell parameters | |
| Count | |
| Density | μm-2 |
| Area | μm2 |
| Average length | Mean width of all DCs detected by software, μm |
| Elongation | The absolute value of the difference between the major and minor axes divided by the sum of the major and minor axes, μm |